Science
Mechanism of Action
Acanthopanax Senticosus Root Extract offers antioxidant protection against free radical damage and inhibits lipid peroxide formation. It also provides anti-inflammatory benefits by inhibiting COX-2 and NF-κB pathways, while increasing anti-inflammatory IL-10.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Phlorizin, an Active Ingredient of Eleutherococcus senticosus, Increases Proliferative Potential of Keratinocytes with Inhibition of MiR135b and Increased Expression of Type IV Collagen - PMC (noted slight toxicity to cells in vitro at 0.005%)
Transparency
Dusting Analysis
No information available regarding dusting potential.
The Formula
Formulation
Stability
No specific stability notes provided in the research data.
Safety
Safety Profile
CIR data is insufficient, though it's generally considered safe for topical use and is distinct from Panax ginseng. EWG rates it 'LOW' for cancer, allergies, and developmental toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While reported to offer various skin benefits, the absence of specific clinical efficacy studies with defined concentrations, coupled with an in vitro toxicity finding, suggests more research is needed to determine its optimal use and overall efficacy confidently.
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